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Effects of vaccines in patients with sickle cell disease: a systematic review protocol
INTRODUCTION: Sickle cell disease (SCD) is an inherited haematological disorder caused by a single point mutation (Glub6Val) that promotes polymerisation of haemoglobin S and sickling of erythrocytes. Inflammation, haemolysis, microvascular obstruction and organ damage characterise the highly variab...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875604/ https://www.ncbi.nlm.nih.gov/pubmed/29581211 http://dx.doi.org/10.1136/bmjopen-2017-021140 |