Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation

Biogenesis of iron-sulfur clusters (ISC) is essential to almost all forms of life and involves complex protein machineries. This process is initiated within the mitochondrial matrix by the ISC assembly machinery. Cohort and case report studies have linked mutations in ISC assembly machinery to sever...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferecatu, Ioana, Canal, Frédéric, Fabbri, Lucilla, Mazure, Nathalie M., Bouton, Cécile, Golinelli-Cohen, Marie-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875801/
https://www.ncbi.nlm.nih.gov/pubmed/29596470
http://dx.doi.org/10.1371/journal.pone.0194782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875801/
https://www.ncbi.nlm.nih.gov/pubmed/29596470
http://dx.doi.org/10.1371/journal.pone.0194782

Ejemplares similares