Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies

Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3 (A3) proteins are a family of cytidine deaminases that catalyze the conversion of deoxycytidine (dC) to deoxyuridine (dU) in single-stranded DNA (ssDNA). A3 proteins act in the innate immune response to viral infection by mutati...

Descripción completa

Detalles Bibliográficos
Autores principales: Ziegler, Samantha J., Liu, Chang, Landau, Mark, Buzovetsky, Olga, Desimmie, Belete A., Zhao, Qi, Sasaki, Tomoaki, Burdick, Ryan C., Pathak, Vinay K., Anderson, Karen S., Xiong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875850/
https://www.ncbi.nlm.nih.gov/pubmed/29596531
http://dx.doi.org/10.1371/journal.pone.0195048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875850/
https://www.ncbi.nlm.nih.gov/pubmed/29596531
http://dx.doi.org/10.1371/journal.pone.0195048

Ejemplares similares