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Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy

Microenvironmental acidity is becoming a key target for the new age of cancer treatment. In fact, while cancer is characterized by genetic heterogeneity, extracellular acidity is a common phenotype of almost all cancers. To survive and proliferate under acidic conditions, tumor cells up-regulate pro...

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Detalles Bibliográficos
Autores principales: Iessi, Elisabetta, Logozzi, Mariantonia, Mizzoni, Davide, Di Raimo, Rossella, Supuran, Claudiu T., Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875992/
https://www.ncbi.nlm.nih.gov/pubmed/29295495
http://dx.doi.org/10.3390/metabo8010002