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Constraining Genome-Scale Models to Represent the Bow Tie Structure of Metabolism for (13)C Metabolic Flux Analysis

Determination of internal metabolic fluxes is crucial for fundamental and applied biology because they map how carbon and electrons flow through metabolism to enable cell function. [Formula: see text] C Metabolic Flux Analysis ([Formula: see text] C MFA) and Two-Scale [Formula: see text] C Metabolic...

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Detalles Bibliográficos
Autores principales: Backman, Tyler W. H., Ando, David, Singh, Jahnavi, Keasling, Jay D., García Martín, Héctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875993/
https://www.ncbi.nlm.nih.gov/pubmed/29300340
http://dx.doi.org/10.3390/metabo8010003