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Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX

Hypoxia is a prominent feature of the tumor microenvironment (TME) and cancer cells must dynamically adapt their metabolism to survive in these conditions. A major consequence of metabolic rewiring by cancer cells in hypoxia is the accumulation of acidic metabolites, leading to the perturbation of i...

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Detalles Bibliográficos
Autores principales: McDonald, Paul C., Swayampakula, Mridula, Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876009/
https://www.ncbi.nlm.nih.gov/pubmed/29517989
http://dx.doi.org/10.3390/metabo8010020