Developmentally primed cortical neurons maintain fidelity of differentiation and establish appropriate functional connectivity after transplantation

Repair of complex CNS circuitry will require newly incorporated neurons to become appropriately, functionally integrated. One approach is to direct differentiation of endogenous progenitors in situ, or ex vivo followed by transplantation. Prior studies find that newly incorporated neurons can establ...

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Detalles Bibliográficos
Autores principales: Wuttke, Thomas V., Markopoulos, Foivos, Padmanabhan, Hari, Wheeler, Aaron P., Murthy, Venkatesh N., Macklis, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876138/
https://www.ncbi.nlm.nih.gov/pubmed/29507412
http://dx.doi.org/10.1038/s41593-018-0098-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876138/
https://www.ncbi.nlm.nih.gov/pubmed/29507412
http://dx.doi.org/10.1038/s41593-018-0098-0

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