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NEDDylation antagonizes ubiquitination of proliferating cell nuclear antigen and regulates the recruitment of polymerase η in response to oxidative DNA damage

NEDDylation has been shown to participate in the DNA damage pathway, but the substrates of neural precursor cell expressed developmentally downregulated 8 (NEDD8) and the roles of NEDDylation involved in the DNA damage response (DDR) are largely unknown. Translesion synthesis (TLS) is a damage-toler...

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Detalles Bibliográficos
Autores principales: Guan, Junhong, Yu, Shuyu, Zheng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876183/
https://www.ncbi.nlm.nih.gov/pubmed/28831681
http://dx.doi.org/10.1007/s13238-017-0455-x