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Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines

Cleavage and activation of hemagglutinin (HA) by trypsin-like proteases in influenza A virus (IAV) are essential prerequisites for its successful infection and spread. In host cells, some transmembrane serine proteases such as TMPRSS2, TMPRSS4 and HAT, along with plasmin in the bloodstream, have bee...

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Detalles Bibliográficos
Autores principales: Hayashi, Hideki, Kubo, Yoshinao, Izumida, Mai, Takahashi, Etsuhisa, Kido, Hiroshi, Sato, Ko, Yamaya, Mutsuo, Nishimura, Hidekazu, Nakayama, Kou, Matsuyama, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876233/
https://www.ncbi.nlm.nih.gov/pubmed/29629340
http://dx.doi.org/10.3389/fcimb.2018.00091