Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity

Acetaminophen (APAP) overdose-induced fatal hepatotoxicity is majorly characterized by overwhelmingly increased oxidative stress while enhanced nuclear factor-erythroid 2-related factor 2 (Nrf2) is involved in prevention of hepatotoxicity. Although Licochalcone A (Lico A) upregulates Nrf2 signaling...

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Detalles Bibliográficos
Autores principales: Lv, Hongming, Xiao, Qingfei, Zhou, Junfeng, Feng, Haihua, Liu, Guowen, Ci, Xinxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876234/
https://www.ncbi.nlm.nih.gov/pubmed/29628888
http://dx.doi.org/10.3389/fphar.2018.00147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876234/
https://www.ncbi.nlm.nih.gov/pubmed/29628888
http://dx.doi.org/10.3389/fphar.2018.00147

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