Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes

AIMS/HYPOTHESIS: The aim of this study was to identify genetic variants associated with beta cell function in type 1 diabetes, as measured by serum C-peptide levels, through meta-genome-wide association studies (meta-GWAS). METHODS: We performed a meta-GWAS to combine the results from five studies i...

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Detalles Bibliográficos
Autores principales: Roshandel, Delnaz, Gubitosi-Klug, Rose, Bull, Shelley B., Canty, Angelo J., Pezzolesi, Marcus G., King, George L., Keenan, Hillary A., Snell-Bergeon, Janet K., Maahs, David M., Klein, Ronald, Klein, Barbara E. K., Orchard, Trevor J., Costacou, Tina, Weedon, Michael N., Oram, Richard A., Paterson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876265/
https://www.ncbi.nlm.nih.gov/pubmed/29404672
http://dx.doi.org/10.1007/s00125-018-4555-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876265/
https://www.ncbi.nlm.nih.gov/pubmed/29404672
http://dx.doi.org/10.1007/s00125-018-4555-9

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