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Meta-genome-wide association studies identify a locus on chromosome 1 and multiple variants in the MHC region for serum C-peptide in type 1 diabetes
AIMS/HYPOTHESIS: The aim of this study was to identify genetic variants associated with beta cell function in type 1 diabetes, as measured by serum C-peptide levels, through meta-genome-wide association studies (meta-GWAS). METHODS: We performed a meta-GWAS to combine the results from five studies i...
Autores principales: | Roshandel, Delnaz, Gubitosi-Klug, Rose, Bull, Shelley B., Canty, Angelo J., Pezzolesi, Marcus G., King, George L., Keenan, Hillary A., Snell-Bergeon, Janet K., Maahs, David M., Klein, Ronald, Klein, Barbara E. K., Orchard, Trevor J., Costacou, Tina, Weedon, Michael N., Oram, Richard A., Paterson, Andrew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876265/ https://www.ncbi.nlm.nih.gov/pubmed/29404672 http://dx.doi.org/10.1007/s00125-018-4555-9 |
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