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Discovery of C-3 Tethered 2-oxo-benzo[1,4]oxazines as Potent Antioxidants: Bio-Inspired Based Design, Synthesis, Biological Evaluation, Cytotoxic, and in Silico Molecular Docking Studies

The discovery of C-3 tethered 2-oxo-benzo[1,4]oxazines as potent antioxidants is disclosed. All the analogs 20a-20ab have been synthesized via “on water” ultrasound-assisted irradiation conditions in excellent yields (upto 98%). All the compounds have been evaluated for their in vitro antioxidant ac...

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Detalles Bibliográficos
Autores principales: Sharma, Vashundhra, Jaiswal, Pradeep K., Saran, Mukesh, Yadav, Dharmendra Kumar, Saloni, Mathur, Manas, Swami, Ajit K., Misra, Sanjeev, Kim, Mi-hyun, Chaudhary, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876303/
https://www.ncbi.nlm.nih.gov/pubmed/29629369
http://dx.doi.org/10.3389/fchem.2018.00056