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Evaluation of a dimeric-cRGD peptide for targeted PET-CT imaging of peripheral angiogenesis in diabetic mice
The α(V) β(3) integrin plays an important role in many physiological functions and pathological disorders. α(V) β(3) is minimally expressed in normal quiescent endothelial cells, but significantly upregulated during neovascularization. In this study, we evaluated a (64)Cu-labeled dimeric cRGD tracer...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876368/ https://www.ncbi.nlm.nih.gov/pubmed/29599497 http://dx.doi.org/10.1038/s41598-018-23372-9 |