Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes

We have redesigned probes for in situ proximity ligation assay (PLA), resulting in more efficient localized detection of target proteins. In situ PLA depends on recognition of target proteins by pairs of antibody-oligonucleotide conjugates (PLA probes), which jointly give rise to DNA circles that te...

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Detalles Bibliográficos
Autores principales: Klaesson, Axel, Grannas, Karin, Ebai, Tonge, Heldin, Johan, Koos, Björn, Leino, Mattias, Raykova, Doroteya, Oelrich, Johan, Arngården, Linda, Söderberg, Ola, Landegren, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876389/
https://www.ncbi.nlm.nih.gov/pubmed/29599435
http://dx.doi.org/10.1038/s41598-018-23582-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876389/
https://www.ncbi.nlm.nih.gov/pubmed/29599435
http://dx.doi.org/10.1038/s41598-018-23582-1

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