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Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes

Current therapies for chronic hepatitis B virus (HBV) infections are effective at decreasing the viral load in serum, but do not lead to viral eradication. Recent studies highlighted the therapeutic or “adjuvant” potential of immune-modulators. Our aim was to explore the direct anti-HBV effect of To...

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Detalles Bibliográficos
Autores principales: Lucifora, Julie, Bonnin, Marc, Aillot, Ludovic, Fusil, Floriane, Maadadi, Sarah, Dimier, Laura, Michelet, Maud, Floriot, Océane, Ollivier, Anaïs, Rivoire, Michel, Ait-Goughoulte, Malika, Daffis, Stéphane, Fletcher, Simon P., Salvetti, Anna, Cosset, François-Loïc, Zoulim, Fabien, Durantel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876392/
https://www.ncbi.nlm.nih.gov/pubmed/29599452
http://dx.doi.org/10.1038/s41598-018-23525-w