Cargando…

Genome-wide identification of natural RNA aptamers in prokaryotes and eukaryotes

RNAs are well-suited to act as cellular sensors that detect and respond to metabolite changes in the environment, due to their ability to fold into complex structures. Here, we introduce a genome-wide strategy called PARCEL that experimentally identifies RNA aptamers in vitro, in a high-throughput m...

Descripción completa

Detalles Bibliográficos
Autores principales: Tapsin, Sidika, Sun, Miao, Shen, Yang, Zhang, Huibin, Lim, Xin Ni, Susanto, Teodorus Theo, Yang, Siwy Ling, Zeng, Gui Sheng, Lee, Jasmine, Lezhava, Alexander, Ang, Ee Lui, Zhang, Lian Hui, Wang, Yue, Zhao, Huimin, Nagarajan, Niranjan, Wan, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876405/
https://www.ncbi.nlm.nih.gov/pubmed/29599443
http://dx.doi.org/10.1038/s41467-018-03675-1