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Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults

Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calorie restriction on healthspan. As such, the use of NAD(+) precursors to augment NAD(+) bioavailability has been proposed as a strategy for improving cardiov...

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Detalles Bibliográficos
Autores principales: Martens, Christopher R., Denman, Blair A., Mazzo, Melissa R., Armstrong, Michael L., Reisdorph, Nichole, McQueen, Matthew B., Chonchol, Michel, Seals, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876407/
https://www.ncbi.nlm.nih.gov/pubmed/29599478
http://dx.doi.org/10.1038/s41467-018-03421-7