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Cell-specific gain modulation by synaptically released zinc in cortical circuits of audition

In many excitatory synapses, mobile zinc is found within glutamatergic vesicles and is coreleased with glutamate. Ex vivo studies established that synaptically released (synaptic) zinc inhibits excitatory neurotransmission at lower frequencies of synaptic activity but enhances steady state synaptic...

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Detalles Bibliográficos
Autores principales: Anderson, Charles T, Kumar, Manoj, Xiong, Shanshan, Tzounopoulos, Thanos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876454/
https://www.ncbi.nlm.nih.gov/pubmed/28887876
http://dx.doi.org/10.7554/eLife.29893