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Suv4-20h1 promotes G1 to S phase transition by downregulating p21(WAF1/CIP1) expression in chronic myeloid leukemia K562 cells

Methylation of histone H4 lysine 20 (H4K20) has been associated with cancer. However, the functions of the histone methyltransferases that trigger histone H4K20 methylation in cancers, including suppressor of variegation 4–20 homolog 1 (Suv4-20h1), remain elusive. In the present study, it was demons...

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Detalles Bibliográficos
Autores principales: Wu, Yupeng, Wang, Yadong, Liu, Ming, Nie, Min, Wang, Ying, Deng, Yexuan, Yao, Bing, Gui, Tao, Li, Xinyu, Ma, Lingling, Guo, Chan, Ma, Chi, Ju, Junyi, Zhao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876467/
https://www.ncbi.nlm.nih.gov/pubmed/29616094
http://dx.doi.org/10.3892/ol.2018.8092