Evaluating Human Immune Responses for Vaccine Development in a Novel Human Spleen Cell-Engrafted NOD-SCID-IL2rγNull Mouse Model

The lack of preclinical models able to faithfully predict the immune responses which are later obtained in the clinic is a major hurdle for vaccines development as it increases markedly the delays and the costs required to perform clinical studies. We developed and evaluated the relevance to human i...

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Detalles Bibliográficos
Autores principales: Ghosn, Stéphanie, Chamat, Soulaima, Prieur, Eric, Stephan, Antoine, Druilhe, Pierre, Bouharoun-Tayoun, Hasnaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876497/
https://www.ncbi.nlm.nih.gov/pubmed/29628927
http://dx.doi.org/10.3389/fimmu.2018.00601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876497/
https://www.ncbi.nlm.nih.gov/pubmed/29628927
http://dx.doi.org/10.3389/fimmu.2018.00601

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