Coming of Age for Autotaxin and Lysophosphatidate Signaling: Clinical Applications for Preventing, Detecting and Targeting Tumor-Promoting Inflammation

A quarter-century after the discovery of autotaxin in cell culture, the autotaxin-lysophosphatidate (LPA)-lipid phosphate phosphatase axis is now a promising clinical target for treating chronic inflammatory conditions, mitigating fibrosis progression, and improving the efficacy of existing cancer c...

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Detalles Bibliográficos
Autores principales: Benesch, Matthew G.K., MacIntyre, Iain T.K., McMullen, Todd P.W., Brindley, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876648/
https://www.ncbi.nlm.nih.gov/pubmed/29543710
http://dx.doi.org/10.3390/cancers10030073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876648/
https://www.ncbi.nlm.nih.gov/pubmed/29543710
http://dx.doi.org/10.3390/cancers10030073

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