A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer

BACKGROUND: Mechanistic models of within-cell signal transduction networks can explain how these networks integrate internal and external inputs to give rise to the appropriate cellular response. These models can be fruitfully used in cancer cells, whose aberrant decision-making regarding their surv...

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Detalles Bibliográficos
Autores principales: Gómez Tejeda Zañudo, Jorge, Scaltriti, Maurizio, Albert, Réka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876695/
https://www.ncbi.nlm.nih.gov/pubmed/29623959
http://dx.doi.org/10.1186/s41236-017-0007-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876695/
https://www.ncbi.nlm.nih.gov/pubmed/29623959
http://dx.doi.org/10.1186/s41236-017-0007-6

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