Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

BACKGROUND: Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of peptides in the blood, liver and kidneys. Since AuNPs seem...

Descripción completa

Detalles Bibliográficos
Autores principales: Kalimuthu, Kalishwaralal, Lubin, Bat-Chen, Bazylevich, Andrii, Gellerman, Gary, Shpilberg, Ofer, Luboshits, Galia, Firer, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://www.ncbi.nlm.nih.gov/pubmed/29602308
http://dx.doi.org/10.1186/s12951-018-0362-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877385/
https://www.ncbi.nlm.nih.gov/pubmed/29602308
http://dx.doi.org/10.1186/s12951-018-0362-1

Ejemplares similares