Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer

BACKGROUND: Alterations in protein glycosylation have been related to malignant transformation and tumour progression. We recently showed that low mRNA levels of Golgi alpha-mannosidase MAN1A1 correlate with poor prognosis in breast cancer patients. METHODS: We analysed the role of MAN1A1 on a prote...

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Detalles Bibliográficos
Autores principales: Legler, Karen, Rosprim, Ricarda, Karius, Tosca, Eylmann, Kathrin, Rossberg, Maila, Wirtz, Ralph M, Müller, Volkmar, Witzel, Isabell, Schmalfeldt, Barbara, Milde-Langosch, Karin, Oliveira-Ferrer, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877434/
https://www.ncbi.nlm.nih.gov/pubmed/29381688
http://dx.doi.org/10.1038/bjc.2017.472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877434/
https://www.ncbi.nlm.nih.gov/pubmed/29381688
http://dx.doi.org/10.1038/bjc.2017.472

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