The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial

BACKGROUND: p38 mitogen-activated protein kinase (MAPK) plays a central role in the regulation and activation of pro-inflammatory mediators. COPD patients have increased levels of activated p38 MAPK, which correlate with increased lung function impairment, alveolar wall inflammation, and COPD exacer...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Naimish R, Cunoosamy, Danen M, Fagerås, Malin, Taib, Ziad, Asimus, Sara, Hegelund-Myrbäck, Tove, Lundin, Sofia, Pardali, Katerina, Kurian, Nisha, Ersdal, Eva, Kristensson, Cecilia, Korsback, Katarina, Palmér, Robert, Brown, Mary N, Greenaway, Steven, Siew, Leonard, Clarke, Graham W, Rennard, Stephen I, Make, Barry J, Wise, Robert A, Jansson, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877500/
https://www.ncbi.nlm.nih.gov/pubmed/29628759
http://dx.doi.org/10.2147/COPD.S150576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877500/
https://www.ncbi.nlm.nih.gov/pubmed/29628759
http://dx.doi.org/10.2147/COPD.S150576

Ejemplares similares