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Role and inhibition of GLI1 protein in cancer

GLI1 is a transcriptional regulator involved in the development of different types of cancer. GLI1 transcriptional activity is regulated within the Hedgehog pathway (canonical activity), but can also be controlled independently (non-canonical activity) in the context of other signaling pathways. Exp...

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Detalles Bibliográficos
Autores principales: Mastrangelo, Eloise, Milani, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877502/
https://www.ncbi.nlm.nih.gov/pubmed/29628779
http://dx.doi.org/10.2147/LCTT.S124483