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Role and inhibition of GLI1 protein in cancer
GLI1 is a transcriptional regulator involved in the development of different types of cancer. GLI1 transcriptional activity is regulated within the Hedgehog pathway (canonical activity), but can also be controlled independently (non-canonical activity) in the context of other signaling pathways. Exp...
Autores principales: | Mastrangelo, Eloise, Milani, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877502/ https://www.ncbi.nlm.nih.gov/pubmed/29628779 http://dx.doi.org/10.2147/LCTT.S124483 |
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