Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF

Mesenchymal stem cells (MSC) provide therapeutic effects in experimental CNS disease models and show promise as cell-based therapies for humans, but their modes of action are not well understood. We previously show that MSC protect rodent neurons against glutamate excitotoxicity in vitro, and in viv...

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Detalles Bibliográficos
Autores principales: Papazian, Irini, Kyrargyri, Vasiliki, Evangelidou, Maria, Voulgari-Kokota, Anda, Probert, Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877512/
https://www.ncbi.nlm.nih.gov/pubmed/29495345
http://dx.doi.org/10.3390/ijms19030651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877512/
https://www.ncbi.nlm.nih.gov/pubmed/29495345
http://dx.doi.org/10.3390/ijms19030651

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