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Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF
Mesenchymal stem cells (MSC) provide therapeutic effects in experimental CNS disease models and show promise as cell-based therapies for humans, but their modes of action are not well understood. We previously show that MSC protect rodent neurons against glutamate excitotoxicity in vitro, and in viv...
Autores principales: | Papazian, Irini, Kyrargyri, Vasiliki, Evangelidou, Maria, Voulgari-Kokota, Anda, Probert, Lesley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877512/ https://www.ncbi.nlm.nih.gov/pubmed/29495345 http://dx.doi.org/10.3390/ijms19030651 |
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