The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis

Expression of aquaporin-1 (AQP1) in endothelial cells is critical for their migration and angiogenesis in cancer. We tested the AQP1 inhibitor, bacopaside II, derived from medicinal plant Bacopa monnieri, on endothelial cell migration and tube-formation in vitro using mouse endothelial cell lines (2...

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Detalles Bibliográficos
Autores principales: Palethorpe, Helen M., Tomita, Yoko, Smith, Eric, Pei, Jinxin V., Townsend, Amanda R., Price, Timothy J., Young, Joanne P., Yool, Andrea J., Hardingham, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877514/
https://www.ncbi.nlm.nih.gov/pubmed/29495367
http://dx.doi.org/10.3390/ijms19030653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877514/
https://www.ncbi.nlm.nih.gov/pubmed/29495367
http://dx.doi.org/10.3390/ijms19030653

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