Integrated Molecular Characterization of Gastrointestinal Stromal Tumors (GIST) Harboring the Rare D842V Mutation in PDGFRA Gene

Gastrointestinal stromal tumors (GIST) carrying the D842V activating mutation in the platelet-derived growth factor receptor alpha (PDGFRA) gene are a very rare subgroup of GIST (about 10%) known to be resistant to conventional tyrosine kinase inhibitors (TKIs) and to show an indolent behavior. In t...

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Detalles Bibliográficos
Autores principales: Indio, Valentina, Astolfi, Annalisa, Tarantino, Giuseppe, Urbini, Milena, Patterson, Janice, Nannini, Margherita, Saponara, Maristella, Gatto, Lidia, Santini, Donatella, do Valle, Italo F., Castellani, Gastone, Remondini, Daniel, Fiorentino, Michelangelo, von Mehren, Margaret, Brandi, Giovanni, Biasco, Guido, Heinrich, Michael C., Pantaleo, Maria Abbondanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877593/
https://www.ncbi.nlm.nih.gov/pubmed/29510530
http://dx.doi.org/10.3390/ijms19030732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877593/
https://www.ncbi.nlm.nih.gov/pubmed/29510530
http://dx.doi.org/10.3390/ijms19030732

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