Selection and Characterization of a DNA Aptamer Specifically Targeting Human HECT Ubiquitin Ligase WWP1

Nucleic acid aptamers hold promise as therapeutic tools for specific, tailored inhibition of protein targets with several advantages when compared to small molecules or antibodies. Nuclear WW domain containing E3 ubiquitin ligase 1 (WWP1) ubiquitin ligase poly-ubiquitinates Runt-related transcriptio...

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Detalles Bibliográficos
Autores principales: Tucker, Wesley O., Kinghorn, Andrew B., Fraser, Lewis A., Cheung, Yee-Wai, Tanner, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877624/
https://www.ncbi.nlm.nih.gov/pubmed/29518962
http://dx.doi.org/10.3390/ijms19030763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877624/
https://www.ncbi.nlm.nih.gov/pubmed/29518962
http://dx.doi.org/10.3390/ijms19030763

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