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Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization

Mammalian respiratory complex I (CI) biogenesis requires both nuclear and mitochondria-encoded proteins and is mostly organized in respiratory supercomplexes. Among the CI proteins encoded by the mitochondrial DNA, NADH-ubiquinone oxidoreductase chain 1 (ND1) is a core subunit, evolutionary conserve...

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Detalles Bibliográficos
Autores principales: Iommarini, Luisa, Ghelli, Anna, Tropeano, Concetta Valentina, Kurelac, Ivana, Leone, Giulia, Vidoni, Sara, Lombes, Anne, Zeviani, Massimo, Gasparre, Giuseppe, Porcelli, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877625/
https://www.ncbi.nlm.nih.gov/pubmed/29518970
http://dx.doi.org/10.3390/ijms19030764