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The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation

The ADAMTS5 metzincin, a secreted zinc-dependent metalloproteinase, modulates the extracellular matrix (ECM) during limb morphogenesis and other developmental processes. Here, the role of ADAMTS5 was investigated by knockdown of zebrafish adamts5 during embryogenesis. This revealed impaired Sonic He...

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Detalles Bibliográficos
Autores principales: Dancevic, Carolyn M., Gibert, Yann, Berger, Joachim, Smith, Adam D., Liongue, Clifford, Stupka, Nicole, Ward, Alister C., McCulloch, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877627/
https://www.ncbi.nlm.nih.gov/pubmed/29518972
http://dx.doi.org/10.3390/ijms19030766