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Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways

Neuroinflammation, characterized marked by microglial activation, plays a very important role in the pathogenesis of Parkinson’s disease (PD). Upon activation, pro-inflammatory mediators are produced by microglia, triggering excessive inflammatory responses and ultimately damaging dopaminergic neuro...

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Detalles Bibliográficos
Autores principales: Chen, Guangxin, Liu, Juxiong, Jiang, Liqiang, Ran, Xin, He, Dewei, Li, Yuhang, Huang, Bingxu, Wang, Wei, Liu, Dianfeng, Fu, Shoupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877682/
https://www.ncbi.nlm.nih.gov/pubmed/29534526
http://dx.doi.org/10.3390/ijms19030821