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A Comprehensive Analysis of Argonaute-CLIP Data Identifies Novel, Conserved and Species-Specific Targets of miR-21 in Human Liver and Hepatocellular Carcinoma

MicroRNAs are ~22 nucleotide RNAs that regulate gene expression at the post-transcriptional level by binding messenger RNA transcripts. miR-21 is described as an oncomiR whose steady-state levels are commonly increased in many malignancies, including hepatocellular carcinoma (HCC). Methods known as...

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Detalles Bibliográficos
Autores principales: Koenig, Aaron Balasingam, Barajas, Juan Martín, Guerrero, María Jose, Ghoshal, Kalpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877712/
https://www.ncbi.nlm.nih.gov/pubmed/29538313
http://dx.doi.org/10.3390/ijms19030851