Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions

Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic transporters that mediate the uptake of many clinically important drugs, including statins from the blood into the liver. Reduced transport function of OATP1B1 and OATP1B3 can lead to clinically relevant drug-drug i...

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Detalles Bibliográficos
Autores principales: Alam, Khondoker, Crowe, Alexandra, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Li, Lang, Yue, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://www.ncbi.nlm.nih.gov/pubmed/29538325
http://dx.doi.org/10.3390/ijms19030855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877716/
https://www.ncbi.nlm.nih.gov/pubmed/29538325
http://dx.doi.org/10.3390/ijms19030855

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