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Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells

Glioblastomas (GBM) are the most frequent and aggressive brain tumors. In these malignancies, progesterone (P4) promotes proliferation, migration, and invasion. The P4 metabolite allopregnanolone (3α-THP) similarly promotes cell proliferation in the U87 human GBM cell line. Here, we evaluated global...

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Detalles Bibliográficos
Autores principales: Zamora-Sánchez, Carmen J., del Moral-Morales, Aylin, Hernández-Vega, Ana M., Hansberg-Pastor, Valeria, Salido-Guadarrama, Ivan, Rodríguez-Dorantes, Mauricio, Camacho-Arroyo, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877725/
https://www.ncbi.nlm.nih.gov/pubmed/29543748
http://dx.doi.org/10.3390/ijms19030864