Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration

Kifunensine, a potent and selective inhibitor of class I α-mannosidases, prevents α-mannosidases I from trimming mannose residues on glycoproteins, thus resulting in oligomannose-type glycans. We report for the first time that through one-time vacuum infiltration of kifunensine in plant tissue, N-li...

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Detalles Bibliográficos
Autores principales: Xiong, Yongao, Li, Qiongyu, Kailemia, Muchena J., Lebrilla, Carlito B., Nandi, Somen, McDonald, Karen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877751/
https://www.ncbi.nlm.nih.gov/pubmed/29562594
http://dx.doi.org/10.3390/ijms19030890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877751/
https://www.ncbi.nlm.nih.gov/pubmed/29562594
http://dx.doi.org/10.3390/ijms19030890

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