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Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration
Kifunensine, a potent and selective inhibitor of class I α-mannosidases, prevents α-mannosidases I from trimming mannose residues on glycoproteins, thus resulting in oligomannose-type glycans. We report for the first time that through one-time vacuum infiltration of kifunensine in plant tissue, N-li...
Autores principales: | Xiong, Yongao, Li, Qiongyu, Kailemia, Muchena J., Lebrilla, Carlito B., Nandi, Somen, McDonald, Karen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877751/ https://www.ncbi.nlm.nih.gov/pubmed/29562594 http://dx.doi.org/10.3390/ijms19030890 |
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