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Distinct Properties of Human M-CSF and GM-CSF Monocyte-Derived Macrophages to Simulate Pathological Lung Conditions In Vitro: Application to Systemic and Inflammatory Disorders with Pulmonary Involvement

Macrophages play a central role in the pathogenesis of inflammatory and fibrotic lung diseases. However, alveolar macrophages (AM) are poorly available in humans to perform in vitro studies due to a limited access to broncho-alveolar lavage (BAL). In this study, to identify the best alternative in v...

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Detalles Bibliográficos
Autores principales: Lescoat, Alain, Ballerie, Alice, Augagneur, Yu, Morzadec, Claudie, Vernhet, Laurent, Fardel, Olivier, Jégo, Patrick, Jouneau, Stéphane, Lecureur, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877755/
https://www.ncbi.nlm.nih.gov/pubmed/29562615
http://dx.doi.org/10.3390/ijms19030894