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Understanding Splenomegaly in Myelofibrosis: Association with Molecular Pathogenesis

Myelofibrosis (MF) is a clinical manifestation of chronic BCR-ABL1-negative chronic myeloproliferative neoplasms. Splenomegaly is one of the major clinical manifestations of MF and is directly linked to splenic extramedullary hematopoiesis (EMH). EMH is associated with abnormal trafficking patterns...

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Detalles Bibliográficos
Autores principales: Song, Moo-Kon, Park, Byeong-Bae, Uhm, Ji-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877759/
https://www.ncbi.nlm.nih.gov/pubmed/29562644
http://dx.doi.org/10.3390/ijms19030898