Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters

The l-arginine/agmatine transporter AdiC is a prokaryotic member of the SLC7 family, which enables pathogenic enterobacteria to survive the extremely acidic gastric environment. Wild-type AdiC from Escherichia coli, as well as its previously reported point mutants N22A and S26A, were overexpressed h...

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Detalles Bibliográficos
Autores principales: Ilgü, Hüseyin, Jeckelmann, Jean-Marc, Colas, Claire, Ucurum, Zöhre, Schlessinger, Avner, Fotiadis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877779/
https://www.ncbi.nlm.nih.gov/pubmed/29558430
http://dx.doi.org/10.3390/ijms19030918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877779/
https://www.ncbi.nlm.nih.gov/pubmed/29558430
http://dx.doi.org/10.3390/ijms19030918

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