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Cooperative CRF and α1 Adrenergic Signaling in the VTA Promotes NMDA Plasticity and Drives Social Stress Enhancement of Cocaine Conditioning

Stressful events rapidly trigger activity-dependent synaptic plasticity, driving the formation of aversive memories. However, it remains unclear how stressful experience affects plasticity mechanisms to regulate appetitive learning, such as intake of addictive drugs. Using rats, we show that cortico...

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Detalles Bibliográficos
Autores principales: Tovar-Díaz, Jorge, Pomrenze, Matthew B., Kan, Russell, Pahlavan, Bahram, Morikawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877815/
https://www.ncbi.nlm.nih.gov/pubmed/29514102
http://dx.doi.org/10.1016/j.celrep.2018.02.039