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Influence of full-length dystrophin on brain volumes in mouse models of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) affects besides muscle also the brain, resulting in memory and behavioral problems. The consequences of dystrophinopathy on gross macroscopic alterations are unclear. To elucidate the effect of full-length dystrophin expression on brain morphology, we used high-reso...

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Detalles Bibliográficos
Autores principales: Kogelman, Bauke, Khmelinskii, Artem, Verhaart, Ingrid, van Vliet, Laura, Bink, Diewertje I., Aartsma-Rus, Annemieke, van Putten, Maaike, van der Weerd, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877835/
https://www.ncbi.nlm.nih.gov/pubmed/29601589
http://dx.doi.org/10.1371/journal.pone.0194636