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Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication

In a search for new potential multitarget anti-HIV compounds from natural products, we have identified in Hypericum scruglii, an endemic and exclusive species of Sardinia (Italy), a potent plant lead. The phytochemical study of the hydroalcoholic extract obtained from its leaves led to the isolation...

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Detalles Bibliográficos
Autores principales: Sanna, Cinzia, Scognamiglio, Monica, Fiorentino, Antonio, Corona, Angela, Graziani, Vittoria, Caredda, Alessia, Cortis, Pierluigi, Montisci, Mariofilippo, Ceresola, Elisa Rita, Canducci, Filippo, Poli, Ferruccio, Tramontano, Enzo, Esposito, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877874/
https://www.ncbi.nlm.nih.gov/pubmed/29601601
http://dx.doi.org/10.1371/journal.pone.0195168