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Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...

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Detalles Bibliográficos
Autores principales: Deo, Pankaj, Chow, Seong H., Hay, Iain D., Kleifeld, Oded, Costin, Adam, Elgass, Kirstin D., Jiang, Jhih-Hang, Ramm, Georg, Gabriel, Kipros, Dougan, Gordon, Lithgow, Trevor, Heinz, Eva, Naderer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877877/
https://www.ncbi.nlm.nih.gov/pubmed/29601598
http://dx.doi.org/10.1371/journal.ppat.1006945