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Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...
Autores principales: | Deo, Pankaj, Chow, Seong H., Hay, Iain D., Kleifeld, Oded, Costin, Adam, Elgass, Kirstin D., Jiang, Jhih-Hang, Ramm, Georg, Gabriel, Kipros, Dougan, Gordon, Lithgow, Trevor, Heinz, Eva, Naderer, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877877/ https://www.ncbi.nlm.nih.gov/pubmed/29601598 http://dx.doi.org/10.1371/journal.ppat.1006945 |
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