Sarcomeric perturbations of myosin motors lead to dilated cardiomyopathy in genetically modified MYL2 mice

Dilated cardiomyopathy (DCM) is a devastating heart disease that affects about 1 million people in the United States, but the underlying mechanisms remain poorly understood. In this study, we aimed to determine the biomechanical and structural causes of DCM in transgenic mice carrying a novel mutati...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Chen-Ching, Kazmierczak, Katarzyna, Liang, Jingsheng, Zhou, Zhiqun, Yadav, Sunil, Gomes, Aldrin V., Irving, Thomas C., Szczesna-Cordary, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877945/
https://www.ncbi.nlm.nih.gov/pubmed/29463717
http://dx.doi.org/10.1073/pnas.1716925115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877945/
https://www.ncbi.nlm.nih.gov/pubmed/29463717
http://dx.doi.org/10.1073/pnas.1716925115

Ejemplares similares